[12] Patent
[11] Patent No.:GC0004587  
[45] Date of Publishing the Grant of the Patent: 31/Dec /2016                32/2016  
Number of the Decision to Grant the Patent:2016/90370
Date of the Decision to Grant the Patent:29/Dec/2016

[21] Application No.:GC 2012-23105

[22] Filing Date:18/12/2012

[30] Priority:

[33] State [32] Priority date [31] Priority No.
FR
20/12/2011
11/03934

[72] Inventors:1- Jean-Luc RENAUD،2- Nicolas PANNETIER،3- Sylvain GAILLARD،4- Jean-Pierre LECOUVE،5- Lucile VAYSSE-LUDOT

[73] Owner: LES LABORATOIRES SERVIER, 35 rue de Verdun, F-92284 , SURESNES Cedex, France

[74] Agent: Suleiman I. Al-Ammar Law Office

  

 

  

[51]IPC:
Int. Cl.7: C07D223/16

[56] Cited Documents:

-WO 2005110993 A1 (SERVIER LAB [FR]; LERESTIF JEAN-MICHEL [FR]; LECOUVE JEAN- PIERRE [FR];) 24 November 2005
-EP 2202225 A1 (SERVIER LAB [FR]) 30 June 2010
-EP 2036892 A1 (SERVIER LAB [FR]) 18 March 2009
-R.CARLSON, T.LEJON, T.LUNDSTEDT AND E. LE
CLOUEREC: “An Optimized Procedure for the
Reductive Amination of Acetophenone by the
Leuckart Reaction,
ACTA CHEMICA SCANDINAVICA,
vol. 47, 1993, pages 1046-1049,
XP002671634,
ISSN: 0904-213X
the whole document
 
Examiner: PH. Bashair Z. AlEnizi

[54] NEW PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID
[57] Abstract: Process for the synthesis of ivabradine of formula (I): addition salts thereof with a pharmaceutically acceptable acid, and hydrates thereof.Medicaments.
No. of claims: 5


 

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